AF488 Anti-Human/Mouse/Rat CD47 Antibody[MIAP410] | E-AB-F1016UL

AF488 Anti-Human/Mouse/Rat CD47 Antibody[MIAP410] | E-AB-F1016UL | Gentaur UK, US & Europe Distribution

Category: Flowcytometry Antibody

Synonyms: Leukocyte surface antigen CD47,Cd47,Integrin-associated protein,IAP

Swissprot Code: Q08722,Q61735,P97829

Application: FCM

Reactivity: Mouse

Host: Rat

Isotype: Rat IgG2b, κ

Research Areas: Cancer, Immunology

Backgroun: CD47, also known as Integrin-Associated Protein (IAP), is a membrane protein of about 50 kD with an IgV-like extracelluluar domain, a five membrane-spanning segment and a short terminal cytoplasmic region. It is widely expressed on many cell types and often associated with beta 3 integrins. It has been reported that CD47 functions as a self marker. Red cells lacking CD47 were rapidly cleared from the bloodstream by splenic macrophages. By binding to SIRPα, CD47 controls hemostatic innate immune functions, such as phagocytosis and cell trafficking.

Concentration: 0.5 mg/mL

Storage: Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

Immunogen: N/A

Buffer: PBS with 0.05% Proclin300, 1% BSA

Purification Method: N/A

Dilution: N/A

Clone: MIAP410

Conjugation: AF488

Moleculair Weight(Calculated): N/A

Moleculair Weight(Observed): N/A