AF647 Anti-Human CD28 Antibody[CD28.2] | E-AB-F1195M

AF647 Anti-Human CD28 Antibody[CD28.2] | E-AB-F1195M | Gentaur UK, US & Europe Distribution

Category: Flowcytometry Antibody

Synonyms: PAS2,MNS,HGpMiX,GYPA,GPSAT

Swissprot Code: P10747

Application: FCM

Reactivity: Mouse

Host: Rat

Isotype: Rat IgG2b, κ

Research Areas: Cancer, Immunology, Stem cells

Backgroun: CD28 is a 44 kD disulfide-linked homodimeric type I glycoprotein. It is a member of the immunoglobulin superfamily and is also known as T44 or Tp44. CD28 is expressed on most T lineage cells, NK cell subsets, and plasma cells. CD28 binds both CD80 and CD86 using a highly conserved motif MYPPY in the CDR3-like loop. CD28 is considered a major co-stimulatory molecule, inducing T lymphocyte activation and IL-2 synthesis, and preventing cell death. In vitro studies indicate that ligation of CD28 on T cells by CD80 and CD86 on antigen presenting cells provides a costimulatory signal required for T cell activation and proliferation.

Concentration: N/A

Storage: Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

Immunogen: N/A

Buffer: PBS with 0.05% Proclin300, 1% BSA

Purification Method: N/A

Dilution: N/A

Clone: CD28.2

Conjugation: AF647

Moleculair Weight(Calculated): N/A

Moleculair Weight(Observed): N/A