AF647 Anti-Mouse CD122 Antibody[5H4] | E-AB-F1029UM

AF647 Anti-Mouse CD122 Antibody[5H4] | E-AB-F1029UM | Gentaur UK, US & Europe Distribution

Category: Flowcytometry Antibody

Synonyms: Interleukin-2 receptor subunit beta,Il2rb,IL-2 receptor subunit beta, IL-2R subunit beta,IL-2RB,High affinity IL-2 receptor subunit beta,p70-75,CD122

Swissprot Code: P16297

Application: FCM

Reactivity: Mouse

Host: Rat

Isotype: Rat IgG2b, κ

Research Areas: Immunology, Signal transduction, Stem cells

Backgroun: CD122 is a 70-75 kD IL-2 receptor β chain also known as IL-2Rβ, which is also shared by the IL-15 receptor. It is constitutively expressed by NK cells and at lower levels by T cells, B cells, monocytes, and macrophages. The IL-2Rβ chain can combine with either the common γ subunit (γc, CD132) alone or with the γc subunit and the IL-2Rα subunit (CD25) to generate intermediate or high affinity IL-2 receptor complexes, respectively. CD122 expression levels can be upregulated by activation. The 5H4 antibody does not block IL-2 binding to the IL-2 receptor. CD122 is expressed on murine, but not human, CD8+ Tregs involved in the maintenance of T cell homeostasis.

Concentration: 0.5 mg/mL

Storage: Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

Immunogen: N/A

Buffer: PBS with 0.05% Proclin300, 1% BSA

Purification Method: N/A

Dilution: N/A

Clone: 5H4

Conjugation: AF647

Moleculair Weight(Calculated): N/A

Moleculair Weight(Observed): N/A