AFN-1252 | B3338

AFN-1252 is a potent inhibitor of enoyl-acyl carrier protein reductase (FabI). Inhibits all clinical isolates of Staphylococcus aureus (n = 502) and Staphylococcus epidermidis (n = 51) tested, including methicillin (meticillin)-resistant isolates, at concentrations of

AFN-1252 is a potent inhibitor of enoyl-acyl carrier protein reductase (FabI). Inhibits all clinical isolates of Staphylococcus aureus (n = 502) and Staphylococcus epidermidis (n = 51) tested, including methicillin (meticillin)-resistant isolates, at concentrations of

B3338 | AFN-1252 DataSheet

Alternate Name/Synonyms: AFN1252 (E)-N-methyl-N-((3-methylbenzofuran-2-yl)methyl)-3-(7-oxo-5,6,7,8-tetrahydro-1,8-naphthyridin-3-yl)acrylamide AFN12520000

Appearance: White to off-white solid

Formulation:

CAS Number: 620175-39-5

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₂H₂₁N₃O₃

Molecular Weight: 375.43

Cell-Permeable?: TRUE

Purity: ≥98%

Solubilities: 5 mg/ml DMSO

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Country of Origin: USA

Tag Line: A potent inhibitor of enoyl-acyl carrier protein reductase (FabI)

MDL Number:

PubChem CID: 10407120

SMILES: O=C(N(C)CC1=C(C)C2=CC=CC=C2O1)/C=C/C3=CC(CC4)=C(N=C3)NC4=O

InChi: InChI=1S/C22H21N3O3/c1-14-17-5-3-4-6-18(17)28-19(14)13-25(2)21(27)10-7-15-11-16-8-9-20(26)24-22(16)23-12-15/h3-7,10-12H,8-9,13H2,1-2H3,(H,23,24,26)/b10-7+

InChi Key: QXTWSUQCXCWEHF-JXMROGBWSA-N