AG-1296 | 2376

Cell-permeable. A potent inhibitor of PDGF receptor kinase (IC₅₀ = 1 µM), c-kit and FGF kinase. Induces apoptosis in H526, small-cell lung cancer cells.

AG-1296 is a potent inhibitor of PDGF receptor kinase (IC₅₀ = 1 µM), c-kit and FGF kinase.

2376 | AG-1296 DataSheet

Alternate Name/Synonyms: 6,7-Dimethoxy-3-phenylquinoxaline; Tyrphostin AG-1296

Appearance: Yellow solid

Formulation: N/A

CAS Number: 146535-11-7

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₆H₁₄N₂O₂

Molecular Weight: 266.29

Cell-Permeable?: Yes

Purity: ≥98% by TLC

Solubilities: DMSO

Handling: Protect from light and air

Country of Origin: USA

Tag Line: A potent PDGF receptor kinase inhibitor

MDL Number: MFCD00270913

PubChem CID: 2049

SMILES: COC1=C(C=C2C(=C1)N=CC(=N2)C3=CC=CC=C3)OC

InChi: InChI=1S/C16H14N2O2/c1-19-15-8-12-13(9-16(15)20-2)18-14(10-17-12)11-6-4-3-5-7-11/h3-10H,1-2H3

InChi Key: QNOXYUNHIGOWNY-UHFFFAOYSA-N