AGP-2 polyclonal Antibody | BS60097

AGP-2 polyclonal Antibody | BS60097 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB IHC

Application Range: WB: 1:500~1:1000 IHC: 1:50~1:200

Background: AGP (a 1-acid Glycoprotein) is an acute phase plasma protein synthesized by the liver. It functions to regulate the interaction between blood cells and endothelial cells, and together with haptoglobin and C reactive protein, it also mediates the extravasation of cells during infection and inflammation. Expression of AGP is induced by acute-phase stimulatory agents such as bacterial lipopolysaccharides. AGP has a high affinity, low capacity binding for basic drugs at physiological pH. In human plasma, AGP is found at levels of 0.5-1.4 mg/ml, though this is elevated during acute inflammation, and, as a result, levels of this protein can be used to diagnose inflammatory conditions. Multiple AGP genes exist, including AGP-1, AGP-2, AGP-3 and AGP-8. AGP-1 and AGP-2 contain five and six potential N-glycosylation sites, respectively. Abnormal expression of the APG-1 gene is linked to sarcoidosis and other immunogenetic diseases, while mutations in the APG-2 gene are associated with different types of carcinomas.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: AGP-2 polyclonal Antibody detects endogenous levels of AGP-2 protein.

Molecular Weight: ~ 24, 45 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Alpha-1-acid glycoprotein 2; AGP 2; Orosomucoid-2; Orosomucoid 2; Orosomucoid2; OMD 2; OMD2; ORM2; ORM-2; AGP2

Immunogen: A synthetic peptide corresponding to residues in Human AGP-2.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: