AGPAT2 polyclonal Antibody | BS6318

AGPAT2 polyclonal Antibody | BS6318 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse

Application: WB IF

Application Range: WB 1:500 - 1:2000 IF 1:50 - 1:100

Background: Phosphatidic acid and lysophosphatidic acid are phospholipids involved in lipid biosynthesis and signal transduction. LPAAT-β (lysophosphatidic acid acyltransferase, beta), also known as AGPAT2, BSCL, BSCL1, LPAAB or 1-AGPAT2 (1-acylglycerol-3-phosphate O-acyltransferase 2), is a multi-pass membrane protein localized to the endoplasmic reticulum that catalyzes the synthesis of phosphatidic acid from lysophosphatidic acid. Predominantly expressed in heart and liver, LPAAT-β belongs to the LPAAT family of proteins that have a well-known role in lipid biosynthesis. In addition, LPAAT family members may also play a role in tumor progression. Mutations in the gene encoding LPAAT-β can result in the autosomal recessive disorder CGL1 (congenital generalized lipodystrophy type 1) . CGL1, also known as Berardinelli-Seip congenital lipodystrophy type 1 (BSCL1), is a disorder characterized by insulin resistance, early onset of diabetes, hepatic steatosis, scarcity of adipose tissue and hypertriglyceridemia.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: AGPAT2 polyclonal Antibody detects endogenous levels of AGPAT2 protein.

Molecular Weight: ~ 31 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: 1-acyl-sn-glycerol-3-phosphate acyltransferase beta ; 1-acylglycerol-3-phosphate O-acyltransferase 2; 1-AGP acyltransferase 2; 1-AGPAT 2; Lysophosphatidic acid acyltransferase beta; LPAAT-beta; AGPAT2

Immunogen: Recombinant full length Human AGPAT2.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: