AIF1 (His-tagged), human recombinant | 7888

Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation.

7888 | AIF1 His-tagged human recombinant DataSheet

Biomolecule/Target: AIF1

Synonyms: Allograft inflammatory factor 1, Ionized calcium-binding adapter molecule 1, Protein G1, IBA1

Alternates names: Allograft inflammatory factor 1, Ionized calcium-binding adapter molecule 1, Protein G1, IBA1

Taglines: Actin-binding protein that enhances membrane ruffling and RAC activation.

NCBI Gene ID #: 6387

NCBI Gene Symbol: SDF1B

Gene Source: Human

Accession #: P48061

Recombinant: Yes

Source: E. coli

Purity by SDS-PAGEs: 98%

Assay: SDS-PAGE

Purity: N/A

Assay #2: N/A

Endotoxin Level: N/A

Activity (Specifications/test method): N/A

Biological activity: Determined by its ability to chemoattract human peripheral T cells activated with PHA and IL-2 using a concentration range of 20-80 ng/ml.

Results: N/A

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 8.5 kDa

Concentration: 0.5 mg/ml

Appearance: Liquid

Physical form description: Liquid

Reconstitution Instructions: Reconstitute in HO to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or –20°C for future use.

Amino acid sequence: N/A