AIPL1 monoclonal Antibody | MB62074

AIPL1 monoclonal Antibody | MB62074 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human, Monkey, Mouse, Rat, Dog

Application: FC, IF, WB

Application Range: WB 1:500~2000, IF 1:100, FLOW 1:100

Background: Leber congenital amaurosis (LCA) accounts for at least 5% of all inherited retinal disease and is the most severe inherited retinopathy with the earliest age of onset. Individuals affected with LCA are diagnosed at birth or in the first few months of life with severely impaired vision or blindness, nystagmus and an abnormal or flat electroretinogram. The photoreceptor/pineal -expressed gene, AIPL1, encoding aryl-hydrocarbon interacting protein-like 1, was mapped within the LCA4 candidate region. The protein contains three tetratricopeptide motifs, consistent with nuclear transport or chaperone activity. AIPL1 mutations may cause approximately 20% of recessive LCA. [provided by RefSeq]

Storage & Stability: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Specificity: aryl hydrocarbon receptor interacting protein like 1

Molecular Weight: 43.7 kDa (Predicted)

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: AIPL2; LCA4

Immunogen: Full length human recombinant protein of human AIPL1 (NP_055151) produced in HEK293T cell.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Pathway: N/A