AKT1S1 Antibody | 26-278

AKT1S1 Antibody | 26-278 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human AKT1S1.

Research Area: Other

Tested Application: E, WB

Application: AKT1S1 antibody can be used for detection of AKT1S1 by ELISA at 1:62500. AKT1S1 antibody can be used for detection of AKT1S1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50, 000 - 100, 000.

Specificiy: N/A

Positive Control 1: 293T Cell Lysate

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: 27 kDa

Validation: N/A

Isoform: N/A

Purification: Antibody is purified by peptide affinity chromatography method.

Clonality: Polyclonal

Clone: N/A

Isotype: N/A

Conjugate: Unconjugated

Physical State: Liquid

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Concentration: batch dependent

Storage Condition: For short periods of storage (days) store at 4˚C. For longer periods of storage, store AKT1S1 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.

Alternate Name: AKT1S1, Lobe, MGC2865, PRAS40

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: AKT1S1 may play an important role in phosphatidylinositol 3-kinase (PI3K) -AKT1 survival signaling. It is the substrate for AKT1 phosphorylation, but can also be activated by AKT1-independent mechanisms. Its role in survival signaling pathways may be modulated by oxidative stress. AKT1S1 may also play a role in nerve growth factor-mediated neuroprotection.AKT1S1 is a proline-rich substrate of AKT (MIM 164730) that binds 14-3-3 protein (see YWHAH, MIM 113508) when phosphorylated (Kovacina et al., 2003 [PubMed 12524439]) .