LBD
AKTIP Antibody (C-term) [APR14909G]
- SKU:
- LBD-APR14909G
- Availability:
- Usually ships in 5 working days
Description
AKTIP Antibody (C-term) [APR14909G] | Gentaur UK, US & Europe Distribution
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H
Specificity: This AKTIP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 262-288 amino acids from the C-terminal region of human AKTIP.
Cellular Localisation: Cytoplasm. Cell membrane; Peripheral membrane protein
Molecular Weight: 33128
Clone: Polyclonal
Gene Name: AKTIP (HGNC:16710)
Gene ID: 64400
Function: Component of the FTS/Hook/FHIP complex (FHF complex) (PubMed:32073997) . The FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting complex (the HOPS complex) . Regulates apoptosis by enhancing phosphorylation and activation of AKT1. Increases release of TNFSF6 via the AKT1/GSK3B/NFATC1 signaling cascade. FHF complex promotes the distribution of AP-4 complex to the perinuclear area of the cell (PubMed:32073997) .
Summary: N/A
Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Application: WB
Dilution: WB--1:1000
Synonyms: AKT-interacting protein, Ft1, Fused toes protein homolog, AKTIP, FTS