ALDH2 Antibody| F40217-0.08ML/F40217-0.4ML/R31184/RQ5101

ALDH2 Antibody| F40217-0.08ML/F40217-0.4ML/R31184/RQ5101 | Gentaur UK, US & Europe Distribution

Background: This protein belongs to the aldehyde dehydrogenase family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of this enzyme, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50% of Orientals have only the cytosolic isozyme, missing the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among Orientals than among Caucasians could be related to the absence of the mitochondrial isozyme. This gene encodes a mitochondrial isoform, which has a low Km for acetaldehydes, and is localized in mitochondrial matrix.

Format: Purified

Clone: 138CT22.3.8

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Isotype: Mouse IgG1, k

Species Reactivity: Human

Predicted Spacies Reactivity: N/A

Application: IHC, FACS, IF, WB, ELISA

Application Details: Western blot: 1:1000, IHC (Paraffin): 1:50-1:100, Flow Cytometry: 1:10-1:50, Immunofluorescence: 1:10-1:50

Application Note: Titration of the ALDH2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Status: Available

Buffer: N/A

Limitation: This ALDH2 antibody is available for research use only.

Purity: Purified

Immunogen: This ALDH2 antibody was produced from a mouse immunized with ALDH2 recombinant protein.

Storage: Aliquot the ALDH2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Localization: N/A