Description
Allicin is a natural product isolated from garlic (Allium sativum) that exhibits many biological effects including antioxidative, anticancer, antimicrobial, and antifungal activities. Allicin (5-10 µM) dose-dependently inhibits cell adhesion, invasion, and migration in lung adenocarcinoma cell lines A549 and H1299. It also alters the balance of tissue inhibitors of matrix metalloproteinases (TIMPs) and matrix metalloproteinases (MMPs), decreases phosphorylation of Akt, and decreases PI3K/Akt signaling.
Allicin is a natural product isolated from garlic (Allium sativum) that exhibits many biological effects including antioxidative, anticancer, antimicrobial, and antifungal activities. Allicin (5-10 µM) dose-dependently inhibits cell adhesion, invasion, and migration in lung adenocarcinoma cell lines A549 and H1299. It also alters the balance of tissue inhibitors of matrix metalloproteinases (TIMPs) and matrix metalloproteinases (MMPs), decreases phosphorylation of Akt, and decreases PI3K/Akt signaling.
Alternate Name/Synonyms: 3-prop-2-enylsulfinylsulfanylprop-1-ene; 2-propene-1-sulfinothioic acid, S-2-propen-1-yl ester; S-allyl prop-2-ene-1-sulfinothioate
Appearance: Oil
Formulation:
CAS Number: 539-86-6
Structure Available?: True
Peptide sequence:
Salt Form: false
Molecular Formula: C₆H₁₀OS₂
Molecular Weight: 162.27
Cell-Permeable?: True
Purity: ≥98%
Solubilities: Soluble in Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone in 0
Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Country of Origin: USA
Tag Line: An active component of garlic with antibacterial, antifungal, antioxidative and anticancer activities
MDL Number: MFCD00468100
PubChem CID: 65036
SMILES: C=CCSS(=O)CC=C
InChi: InChI=1S/C6H10OS2/c1-3-5-8-9(7)6-4-2/h3-4H,1-2,5-6H2
InChi Key: JDLKFOPOAOFWQN-UHFFFAOYSA-N
Additional Information
Storage Condition: |
-80ºC |
Shipping Condition: |
Dry Ice |
Shelf Life: |
36 months |