Alogliptin benzoate | 9656

Alogliptin benzoate is a potent, selective inhibitor of DPP-4 (dipeptidyl peptidase-4) with an IC₅₀ of <10 nM. Displays greater than 10,000-fold selectivity over DPP-8 and DPP-9. An anti-diabetic agent for treatment of type 2 diabetes.

Alogliptin benzoate is a potent, selective inhibitor of DPP-4 (dipeptidyl peptidase-4) with an IC₅₀ of <10 nM. Displays greater than 10,000-fold selectivity over DPP-8 and DPP-9. An anti-diabetic agent for treatment of type 2 diabetes.

9656 | Alogliptin benzoate DataSheet

Alternate Name/Synonyms: 2-[[6-[(3R)-3-Amino-1-piperidinyl]-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-pyrimidinyl]methyl]benzonitrile benzoate; SYR-322, Nesina, SYR322

Appearance: White to off-white solid

Formulation: N/A

CAS Number: 850649-62-6

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₈H₂₁N₅O₂.C₇H₆O₂

Molecular Weight: 461.52

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO (>10 mg/ml)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A potent, selective DPP-4 (dipeptidyl peptidase-4) inhibitor

MDL Number: N/A

PubChem CID: 16088021

SMILES: CN1C(=O)C=C(N(C1=O)CC2=CC=CC=C2C#N)N3CCCC(C3)N.C1=CC=C(C=C1)C(=O)O

InChi: InChI=1S/C18H21N5O2.C7H6O2/c1-21-17(24)9-16(22-8-4-7-15(20)12-22)23(18(21)25)

InChi Key: KEJICOXJTRHYAK-XFULWGLBSA-N