400
Alpha Synuclein Antibody (pSer129)- Alkaline Phosphatase
- SKU:
 - 400-SPC-742D-ALP-GEN
 - Availability:
 - IN STOCK
 
Additional Information
Size:  | 
                                                    100 µl  | 
                                                
Target:  | 
                                                    Alpha Synuclein pSer129  | 
                                                
Conjugate:  | 
                                                    Alkaline Phosphatase  | 
                                                
Research Area:  | 
                                                    Neuroscience | Neurodegeneration | Alzheimer's Disease | Tangles & Tau | Neuroscience | Neurodegeneration | Parkinson's Disease | Synuclein  | 
                                                
Alternative Name:  | 
                                                    Phospho anti-alpha Synuclein (S129) antibody, Alpha-synuclein (phospho S129) antibody, alpha Synuclein (phospho Ser129) antibody, alpha-Synuclein Phospho Ser129 Antibody, phospho-α-Synuclein (Ser129) Antibody, Alpha synuclein antibody, Alpha synuclei  | 
                                                
Category:  | 
                                                    Antibodies  | 
                                                
Product Type:  | 
                                                    Polyclonal Antibody  | 
                                                
Immunogen:  | 
                                                    Synthetic peptide of Human Alpha Synuclein pSer129 (40-140 aa), conjugated to Keyhole Limpet Haemocyanin (KLH).  | 
                                                
Immunogen Species:  | 
                                                    Human  | 
                                                
Applications:  | 
                                                    WB, ELISA, ICC/IF, IHC  | 
                                                
Host:  | 
                                                    Rabbit  | 
                                                
Isotype:  | 
                                                    N/A  | 
                                                
Species Reactivity:  | 
                                                    Human, Mouse, Rat  | 
                                                
Antibody Dilution:  | 
                                                    WB (1:1000); ICC/IF (1:500); optimal dilutions for assays should be determined by the user.  | 
                                                
Purification:  | 
                                                    Peptide Affinity Purified  | 
                                                
Storage Buffer:  | 
                                                    PBS pH 7.4, 50% glycerol, 0.09% Sodium Azide  | 
                                                
Concentration:  | 
                                                    0.5mg/mL  | 
                                                
Specificity:  | 
                                                    Binds to phosphorylated serine 129 on alpha synuclein. Does not detect unphosphorylated serine 129 alpha synuclein. Detects bands at 100, 75, 45, 15 kDa. Bands above 15 kDa are oligomers.  | 
                                                
Storage:  | 
                                                    -20ºC  | 
                                                
Shipping:  | 
                                                    Blue Ice or 4ºC  | 
                                                
Certificate of Analysis:  | 
                                                    A 1:1000 dilution of SPC-742 was sufficient for detection of Alpha Synuclein pSer129 in 15 µg of human brain cell lysates by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.  | 
                                                
Cellular Localization:  | 
                                                    Cytoplasm, Membrane, Nucleus, Cell Junction, Synapse, Secreted  | 
                                                
Tissue Specificity:  | 
                                                    Highly expressed in brain (presynaptic nerve terminals) but is also expressed in low concentrations in all tissues examined except in liver.  | 
                                                
Accession Number:  | 
                                                    NP_000336.1  | 
                                                
Gene ID:  | 
                                                    6622  | 
                                                
Swiss-Prot:  | 
                                                    P37840  | 
                                                
Field of Use:  | 
                                                    For in vitro research use only.  |