ALPK1 polyclonal Antibody | BS61558

ALPK1 polyclonal Antibody | BS61558 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human

Application: WB

Application Range: WB: 1:500~1:1000

Background: The phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions in eukaryotes, including cell division, homeostasis and apoptosis. α-protein kinase 1, also known as ALPK1, LAK or KIAA1527, is a 1,244 amino acid protein that contains one α-type protein kinase domain and belongs to the protein kinase superfamily. Expressed at high levels in liver, α-protein kinase 1 recognizes and phosphorylates specific phosphorylation sites that are surrounded by peptides which have an å-helical conformation. One of the targets of å-protein kinase 1 is Myosin I and, via its ability to phosphorylate Myosin I, α-protein kinase 1 is thought to play an important role in the apical trafficking of vesicles carrying raft-associated sucrase-isomaltase (SI) .

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: ALPK1 polyclonal Antibody detects endogenous levels of ALPK1 protein.

Molecular Weight: ~ 139 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Alpha-protein kinase 1; Chromosome 4 kinase; Lymphocyte alpha-protein kinase

Immunogen: Synthetic peptide, corresponding to amino acids 11-55 of Human ALPK1

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE)

Pathway: Immune Cell Signaling,