Description
ALPP monoclonal Antibody | MB0158 | Gentaur UK, US & Europe Distribution
Host: Mouse
Reactivity: Human
Application: WB ICC
Application Range: WB: 1:500~1000 ICC: 1:100~300
Background: There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific) . The first three are located together on chromosome 2 while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme, also referred to as the heat stable form, that is expressed primarily in the placenta although it is closely related to the intestinal form of the enzyme as well as to the placental-like form. The coding sequence for this form of alkaline phosphatase is unique in that the 3´ untranslated region contains multiple copies of an Alu family repeat. In addition, this gene is polymorphic and three common alleles (type 1, type 2 and type 3) for this form of alkaline phosphatase have been well characterized.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: This Antibody detects endogenous levels of Placental alkaline phosphatase and does not cross-react with related proteins
Molecular Weight: Predicted band size:76KDa Observed band size:76KDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: Alkaline phosphatase Regan isozyme; Placental alkaline phosphatase 1; ALP; PALP; PLAP; PLAP-1; ALPP
Immunogen: Recombinant full length Human ALPP.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway: