AMACR (C-terminus) monoclonal Antibody | MB0099

AMACR (C-terminus) monoclonal Antibody | MB0099 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Rat

Application: WB ICC

Application Range: WB: 1:1000 ICC: 1:50~200

Background: P504S, also known as AMACR (a-methylacyl-CoA racemase), 2-methylacyl-CoA racemase or RACE, is an enzyme belonging to the caiB/baiF CoA-transferase family. Localizing to the peroxisome and mitochondrion, P504S plays a role in the metabolism of branched-chain fatty acids and bile acid intermediates. More specifically, P504S catalyzes the conversion of pristanoyl-CoA and C27-bile acyl-CoAs to their (S) -stereoisomers which can then be degraded by peroxisomal b-oxidation. Mutations in the gene encoding P504S can lead to AMACR deficiency, a disease characterized by increased concentrations of pristanic acid that is associated with adult onset sensory motor neuropathy.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: This Antibody detects endogenous levels of AMACR and does not cross-react with related proteins

Molecular Weight: Predicted band size:42KDa Observed band size:42KDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Alpha-methylacyl-CoA racemase; 2-methylacyl-CoA racemase; AMACR

Immunogen: Synthetic peptide, corresponding to the C-terminus of Human AMACR.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: