AMACR / p504S Antibody [AMACR/1723] | 33-611

AMACR / p504S Antibody [AMACR/1723] | 33-611 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human

Homology: N/A

Immunogen: A recombinant human protein was used as the immunogen for the AMACR antibody.

Research Area: Cancer, Cell Cycle, Obesity, Signal Transduction

Tested Application: WB, IHC-P, IF

Application: Immunohistology (FFPE) : 1-2 ug/ml for 30 minutes at RT
IF: 1-2 ug/ml
Optimal dilution of the AMACR antibody should be determined by the researcher.

Specificiy: N/A

Positive Control 1: N/A

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: N/A

Validation: N/A

Isoform: N/A

Purification: Protein G affinity chromatography

Clonality: Monoclonal

Clone: AMACR/1723

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.1 mg/ml BSA and 0.05% sodium azide

Concentration: 0.2 mg/mL

Storage Condition: Aliquot and Store at 2-8˚C. Avoid freez-thaw cycles.

Alternate Name: Alpha-methylacyl-CoA racemase, 2-methylacyl-CoA racemase, AMACR

User Note: Optimal dilutions for each application to be determined by the researcher

BACKGROUND: AMACR, also known as p504S is an enzyme that is involved in bile acid biosynthesis and beta-oxidation of branched-chain fatty acids. It is expressed in cells of premalignant high-grade prostatic intraepithelial neoplasia (HGPIN) and prostate adenocarcinoma. The majority of the carcinoma cells show a distinct granular cytoplasmic staining reaction. AMACR is present at low or undetectable levels in glandular epithelial cells of normal prostate and benign prostatic hyperplasia. A spotty granular cytoplasmic staining is seen in a few cells of the benign glands.