AMBP | Bikunin (50 µl) | AS06 173

AMBP | Bikunin (50 µl) | AS06 173 | Gentaur UK, US & Europe Distribution

Immunogen: human recombinant bikunin, UniProt: P02760, cleavage product no. PRO_0000017887

Host: Rabbit

Conjugation: N/A

Clonality: Polyclonal

Isotype: N/A

Purity: Serum

Format: Lyophilized

Tested Application: ELISA (ELISA), Western blot (WB)

Related Products: AS04 040 | anti-bikunin (mice), rabbit antibodiesAS04 039 | anti-bikunin (rat), rabbit antibodiesSecondary antibodies

Recommended Dilutions: 1 : 2000 (ELISA), 1 : 2000 (WB)

Molecular weight: free bikunin 60-80 kDa

Confirmed Reactivity: Human

Predicted Reactivity: Bovine, Pig, Primates

Not reactive in: No confirmed exceptions from predicted reactivity are currently known

Additional Information: N/A

Background: Bikunin is a Kunitz-type protease inhibitor synthesized in the liver. The AMBP gene resides in the lipocalin cluster and encodes alpha-1-microglobulin together with a Kunitz-type proteinase inhibitor, bikunin. The gene is translated into the alpha-1-microglobulin-bikunin precursor, which is subsequently cleaved and the two proteins are secreted to the blood separately. Bikunin is found in blood and tissues both in free form and associated with heavy chains forming the inter-alpha-inhibitor family of proteins. Bikunin is a protease inhibitor, a component of extracellular matrix and exhibits anti-inflammatory activity in protection against cancer and inflammation.

Reconstitution: For reconstitution add 50 µl of sterile water

Storage: Store lyophilized/reconstituted at -20°C; once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.

TAIR Nnumbre: N/A

Category: Other proteins

Research Area: Cell Biology