Ambroxol hydrochloride | 9688

Ambroxol is a sodium channel blocker and mucolytic agent with antioxidant, anti-viral and anti-inflammatory properties. Inhibits tetrodotoxin (TTX)-resistant channels more potently than TTX-sensitive subtypes (IC₅₀ values for tonic block are 35.2 and 111.5 μM respectively). More recently, it has been shown that Ambroxol induces a modest level neuron regrowth in mice with optic nerve lesions.

Ambroxol is a sodium channel blocker and mucolytic agent with antioxidant, anti-viral and anti-inflammatory properties. Inhibits tetrodotoxin (TTX)-resistant channels more potently than TTX-sensitive subtypes (IC₅₀ values for tonic block are 35.2 and 111.5 μM respectively). More recently, it has been shown that Ambroxol induces a modest level neuron regrowth in mice with optic nerve lesions.

9688 | Ambroxol hydrochloride DataSheet

Alternate Name/Synonyms: trans-4-[[(2-Amino-3,5-dibromophenyl)methyl]amino]cyclohexanol hydrochloride

Appearance: White solid

Formulation: N/A

CAS Number: 23828-92-4

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: HCl

Molecular Formula: C₁₃H₁₈Br₂N₂O.HCl

Molecular Weight: 414.57

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO (~20 mg/ml)

Handling: Protect from air and moisture

Country of Origin: USA

Tag Line: A sodium channel blocker and mucolytic agent

MDL Number: MFCD00078932

PubChem CID: 108013

SMILES: C1CC(CCC1NCC2=CC(=CC(=C2N)Br)Br)O.Cl

InChi: InChI=1S/C13H18Br2N2O.ClH/c14-9-5-8(13(16)12(15)6-9)7-17-10-1-3-11(18)4-2-10;/h5-6,10-11,17-18H,1-4,7,16H2;1H

InChi Key: QNVKOSLOVOTXKF-UHFFFAOYSA-N