AMG-900 | B1343

AMG-900 is a highly sensitive and orally bioavailable inhibitor of Aurora Kinase with IC50 values of 5 nmol/L

AMG-900 is a highly sensitive and orally bioavailable inhibitor of Aurora Kinase with IC50 values of 5 nmol/L

B1343 | AMG-900 DataSheet

Alternate Name/Synonyms: N-[4-[3-(2-aminopyrimidin-4-yl)pyridin-2-yl]oxyphenyl]-4-(4-methylt hiophen-2-yl)phthalazin-1-amine

Appearance: Solid

Formulation: N/A

CAS Number: 945595-80-2

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C28H21N7OS

Molecular Weight: 503.58

Cell-Permeable?: Yes

Purity: >98%

Solubilities: DMSO > 10 mM

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A highly sensitive and orally bioavailable inhibitor of Aurora Kinase

MDL Number: MFCD18633194

PubChem CID: 24856041

SMILES: CC1=CSC(=C1)C2=NN=C(C3=CC=CC=C32)NC4=CC=C(C=C4)OC5=C(C= CC=N5)C6=NC(=NC=C6)N

InChi: 1S/C28H21N7OS/c1-17-15-24(37-16-17)25-20-5-2-3-6-21(20)26(35-34-25)32-18-8-10-19(11-9-18)36-27-22(7-4-13-30-27)23-12-14-31-28(29)33-23/h2-16H,1H3,(H,32,35)(H2,29,31,33)

InChi Key: IVUGFMLRJOCGAS-UHFFFAOYSA-N