AMG-Tie2 | B1612

AMG-Tie2 is a highly potent, non-selective inhibitor of Tie-2

AMG-Tie2 is a highly potent, non-selective inhibitor of Tie-2

B1612 | AMG-Tie2 DataSheet

Alternate Name/Synonyms: AMGTie2; AMG Tie2; 4-methyl-3-[3-[2-(methylamino)pyrimidin-4-yl]pyridin-2-yl]oxy-N-[3-(trifluoromethyl)phenyl]benzamide, Tie-2 inhibitor, Tie2 inhibitor

Appearance: Solid

Formulation: N/A

CAS Number: 870223-96-4

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₅H₂₀F₃N₅O₂

Molecular Weight: 479.4

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO (15 mM)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A highly potent, non-selective Tie-2 inhibitor

MDL Number: MFCD16038641

PubChem CID: 16108977

SMILES: CC1=C(C=C(C=C1)C(=O)NC2=CC=CC(=C2)C(F)(F)F)OC3=C(C=CC=N3)C4=NC(=NC=C4)NC

InChi: 1S/C25H20F3N5O2/c1-15-8-9-16(22(34)32-18-6-3-5-17(14-18)25(26,27)28)13-21(15)35-23-19(7-4-11-30-23)20-10-12-31-24(29-2)33-20/h3-14H,1-2H3,(H,32,34)(H,29,31,33)

InChi Key: ZVIWALRWYYSHSU-UHFFFAOYSA-N