Amlexanox | 2336

An anti-allergy, anti-asthma and anti-diabetic agent. Improves obesity-related metabolic dysfunction in mouse models. Increases thermogenesis and weight loss, decreases steatosis and improves insulin sensitivity. Inhibits TANK-binding kinase 1 (TBK1) and IKKe (IC₅₀ =1.2 µM). Clinically useful in treatment of aphthus ulcers.

Almexanos is an anti-allergy, anti-asthma and anti-diabetic agent. Improves obesity-related metabolic dysfunction in mouse models. Increases thermogenesis and weight loss, decreases steatosis and improves insulin sensitivity.

2336 | Amlexanox DataSheet

Alternate Name/Synonyms: 2-Amino-7-(1-methylethyl)-5-oxo-5H-[1]benzopyrano[2,3-b]pyridine-3-carboxylic acid ; AA 673; Amoxanox, CHX 3673

Appearance: White solid

Formulation: N/A

CAS Number: 68302-57-8

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₆H₁₄N₂O₄

Molecular Weight: 298.29

Cell-Permeable?: Yes

Purity: ≥98% by TLC

Solubilities: DMSO (60 mg/ml)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: An anti-allergy, anti-asthma and anti-diabetic agent

MDL Number: MFCD00864790

PubChem CID: 2161

SMILES: CC(C)C1=CC2=C(C=C1)OC3=NC(=C(C=C3C2=O)C(=O)O)N

InChi: InChI=1S/C16H14N2O4/c1-7(2)8-3-4-12-9(5-8)13(19)10-6-11(16(20)21)14(17)18-15(10)22-12/h3-7H,1-2H3,(H2,17,18)(H,20,21)

InChi Key: SGRYPYWGNKJSDL-UHFFFAOYSA-N