AMPKβ1 (1A7) monoclonal Antibody | MB0188

AMPKβ1 (1A7) monoclonal Antibody | MB0188 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human,Mouse,Rat,Monkey

Application: WB ICC IHC IP

Application Range: WB: 1:1000 IP: 1:50~200 ICC: 1:200 IHC: 1:800

Background: AMPKβ1 is a member of the SNF1 kinase family. It is a heterotrimeric protein comprising of an alpha (catalytic), beta (non-catalytic) and gamma (non-catalytic) subunits, 63, 38 and 38kDa respectively.AMPKβ1 regulates fatty acid and sterol synthesis by phosphorylation of acteyl-coA. It also regulates cholesterol synthesis via phosphorylation and in-activation of hydroxymethylglutaryl-CoA reductase.Two isoforms of AMPKβ1 have been found.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: This Antibody detects endogenous levels of AMPKβ1 and does not cross-react with related proteins.

Molecular Weight: Predicted band size:38KDa Observed band size:38KDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: 5'-AMP-activated protein kinase subunit beta-1; AMPK subunit beta-1; AMPKb; PRKAB1; AMPK; AMPK β1

Immunogen: Purified recombinant human AMPKβ1 protein fragments expressed in E.coli.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: Warburg Effect,Insulin &Glucose Signaling,Glutamine Metabolism,