BW
AMPKβ1 (1A7) monoclonal Antibody | MB0188
- SKU:
- BW-MB0188
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- Usually ships in 5 working days
Description
AMPKβ1 (1A7) monoclonal Antibody | MB0188 | Gentaur UK, US & Europe Distribution
Host: Mouse
Reactivity: Human,Mouse,Rat,Monkey
Application: WB ICC IHC IP
Application Range: WB: 1:1000 IP: 1:50~200 ICC: 1:200 IHC: 1:800
Background: AMPKβ1 is a member of the SNF1 kinase family. It is a heterotrimeric protein comprising of an alpha (catalytic), beta (non-catalytic) and gamma (non-catalytic) subunits, 63, 38 and 38kDa respectively.AMPKβ1 regulates fatty acid and sterol synthesis by phosphorylation of acteyl-coA. It also regulates cholesterol synthesis via phosphorylation and in-activation of hydroxymethylglutaryl-CoA reductase.Two isoforms of AMPKβ1 have been found.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: This Antibody detects endogenous levels of AMPKβ1 and does not cross-react with related proteins.
Molecular Weight: Predicted band size:38KDa Observed band size:38KDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: 5'-AMP-activated protein kinase subunit beta-1; AMPK subunit beta-1; AMPKb; PRKAB1; AMPK; AMPK β1
Immunogen: Purified recombinant human AMPKβ1 protein fragments expressed in E.coli.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway: Warburg Effect,Insulin &Glucose Signaling,Glutamine Metabolism,