AMPK Activator, D942 | 2341

Cell-permeable. A potent activator of AMPK (AMP-activated protein kinase). The activation of AMPK was achieved through inhibition of NAD(P)H dehydrogenase [quinone] 1 (complex I). D942 increases glucose uptake in L6 myocytes, and inhibits CCL2-induced mTORC1 activity and survivin expression in human prostate cancer PC-3 cells.

D942 is a potent activator of AMPK (AMP-activated protein kinase).

2341 | AMPK Activator, D942 DataSheet

Alternate Name/Synonyms: 5-(3-(4-(2-(4-Fluorophenyl)ethoxy)phenyl)propyl)furan-2-carboxylic acid

Appearance: Light yellow solid

Formulation: N/A

CAS Number: 849727-81-7

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₂H₂₁FO₄

Molecular Weight: 368.4

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO (10 mg/ml)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A potent AMPK activator

MDL Number: N/A

PubChem CID: 16760291

SMILES: C1=CC(=CC=C1CCCC2=CC=C(O2)C(=O)O)OCCC3=CC=C(C=C3)F

InChi: InChI=1S/C22H21FO4/c23-18-8-4-17(5-9-18)14-15-26-19-10-6-16(7-11-19)2-1-3-20-12-13-21(27-20)22(24)25/h4-13H,1-3,14-15H2,(H,24,25)

InChi Key: MPLLLQUZNJSVTK-UHFFFAOYSA-N