AMPK? Antibody | 3108

AMPK beta-1 chain is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (H mgCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. The myristoylation and phosphorylation of this subunit have been shown to affect the enzyme activity and cellular localization of AMPK. This subunit may also serve as an adaptor molecule mediating the association of the AMPK complex.

3108 | AMPK? Antibody DataSheet

Antibody Target: AMPK?

Target Alternative Name: AMPK, 5'-AMP-activated protein kinase, beta-1 subunit, AMP activated protein kinase beta-1 subunit, AMPK beta-1 chain, AMPKb

Tag Line:

Category: AMPK

Host: Rabbit

Isotype: Rabbit IgG

Species Reactivities: Human, mouse

Immunogen Sequence: Synthetic peptide selected from the N-terminal region of human PRKAB1

Accession #: Q9Y478

Gene ID: 5564

Appearance: Colorless liquid

Form: Liquid

Concentration: 0.25 mg/ml

Formulation: 100 µg (0.25 mg/ml) purified rabbit Ig polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

Purification: Affinity purified

Application: ELISA, Western blot, Immunohistochemistry

Positive Control:

Application And Usages: The antibody can be used for ELISA (0.25 µg/ml), Western blotting (0.5 – 2.5 µg/ml) and Immunohistochemistry (2.5-5.0 µg/ml).

Country of Animal Origin: USA

Country of Manufacture: USA

Usage: For Research Use Only! Not to be used in humans.

Handling: The antibody solution should be gently mixed before use.

Western Blot Verified: Verified

Immunocytochemistry Verified: Verified

Immunofluorescence Verified: Not Verified

Immunoprecipitation Verified: Not Verified

FACS Verified: Not Verified

ELISA Verified: Verified

ChIP Verified: Not Verified

Dot Blot Verified: Not Verified

Flow Cytometry Verified: Not Verified