Amprenavir | B2141

Amprenavir is the active metabolite of the pro-drug fosamprenavir. It acts as an antiretroviral HIV Protease Inhibitor. When used alone or in combination therapy with other antiretroviral agents, amprenavir decreases viral load and increases CD4+ cell counts.

Amprenavir is the active metabolite of the pro-drug fosamprenavir. It acts as an antiretroviral HIV Protease Inhibitor. When used alone or in combination therapy with other antiretroviral agents, amprenavir decreases viral load and increases CD4+ cell counts.

B2141 | Amprenavir DataSheet

Alternate Name/Synonyms: N-[(1S,2R)-3-[[(4-aminophenyl)sulfonyl](2-methylpropyl)amino]-2-hydroxy-1-(phenylmethyl)propyl]-carbamic acid, (3S)-tetrahydro-3-furanyl ester; VX-478

Appearance: White to off-white solid

Formulation: N/A

CAS Number: 161814-49-9

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₅H₃₅N₃O₆S

Molecular Weight: 505.63

Cell-Permeable?: Yes

Purity: ≥95% by HPLC

Solubilities: DMSO (~20 mg/ml)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A HIV Protease Inhibitor

MDL Number: MFCD00934214

PubChem CID: 65016

SMILES: CC(C)CN(CC(C(CC1=CC=CC=C1)NC(=O)OC2CCOC2)O)S(=O)(=O)C3=CC=C(C=C3)N

InChi: InChI=1S/C25H35N3O6S/c1-18(2)15-28(35(31,32)22-10-8-20(26)9-11-22)16-24(29)23(14-19-6-4-3-5-7-19)27-25(30)34-21-12-13-33-17-21/h3-11,18,21,23-24,29H,12-17,26H2,1-2H3,(H,27,30)/t21-,23-,24+/m0/s1

InChi Key: YMARZQAQMVYCKC-OEMFJLHTSA-N