Angiotensinogen Polyclonal Antibody | E-AB-40478

Angiotensinogen Polyclonal Antibody | E-AB-40478 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: Aangiotensinogen (serpin peptidase inhibitor clade A member 8), AGT, AI265500, Alpha 1 antiproteinase antitrypsin, Ang, Ang I, Ang II, Ang III, AngII, Angiotensin I, Angiotensin II, Angiotensin III, Angiotensin-3, Angiotensinogen (PAT), Angiotensinogen, ANGT, ANHU, ANRT, AT-2, AT-II, Des-Asp[1]-angiotensin II, PAT, Pre angiotensinogen, Serine (or cysteine) proteinase inhibitor, Serpin A8, Serpin peptidase inhibitor clade A member 8, SERPINA8

Application: WB, IHC

Reactivity: Mouse, Rat

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Cardiovascular, Metabolism, Signal Transduction

Background: Angiotensinogen is a precursor of angiotensin II (Ang II), is expressed and synthesized largely in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. It has a key role in mediating vascular constriction and regulating salt and fluid homeostasis. The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. Mutations in this gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease.

Concentration: 1mg/mL

Storage: Store at -20℃. Avoid freeze / thaw cycles.

Immunogen: Recombinant Mouse Angiotensinogen protein

Buffer: PBS with 0.05% Proclin300, 50% glycerol, pH7.3.

Purification Method: Antigen Affinity Purification

Dilution: WB 1:2000-1:5000 IHC 1:100-1:300

Clone: N/A

Conjugation: N/A

Molecular Weight(Calculated): 52 kDa

Molecular Weight(Observed): 52 kDa