Anisomycin | 1549

An activator of p54 and MAP kinases. Synergistic with growth factors and phorbol esters to superinduce cFas and c-Jun, by acting as a potent signaling agonist. Induces apoptosis in the human monoblastoid cell line.

Anisomycin is an antibiotic that acts as a protein synthesis inhibitor. Also an activator of p54 and MAP kinases.

1549 | Anisomycin DataSheet

Alternate Name/Synonyms: (2R,3S,4S)-2-(4-Methoxybenzyl)-3,4-pyrrolidinediol-3-acetate, 2-[(4-Methoxyphenyl)methyl]-3,4-pyrrolidinediol 3-acetate, Flagecidin

Appearance: White solid

Formulation: N/A

CAS Number: 22862-76-6

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₄H₁₉NO₄

Molecular Weight: 265.3

Cell-Permeable?: yes

Purity: ≥98%

Solubilities: DMSO or EtOH

Handling: Protect from light and moisture

Country of Origin: USA

Tag Line: A MAP kinase activator

MDL Number: MFCD00077650

PubChem CID: 253602

SMILES: CC(=O)OC1C(CNC1CC2=CC=C(C=C2)OC)O

InChi: InChI=1S/C14H19NO4/c1-9(16)19-14-12(15-8-13(14)17)7-10-3-5-11(18-2)6-4-10/h3-6,12-15,17H,7-8H2,1-2H3/t12-,13+,14+/m1/s1

InChi Key: YKJYKKNCCRKFSL-RDBSUJKOSA-N