Anlotinib Hydrochloride | B3336

Anlotinib (AL3818) is a potent oral receptor tyrosine kinase inhibitor targeting vascular endothelial growth factor receptor 2 (VEGFR2) and 3 (VEGFR3), fibroblast growth factor 1–4, platelet-derived growth factor receptor α and β, c-Kit and Ret. Anlotinib exerts inhibitory effects on tumor growth and angiogenesis.

Anlotinib (AL3818) is a potent oral receptor tyrosine kinase inhibitor targeting vascular endothelial growth factor receptor 2 (VEGFR2) and 3 (VEGFR3), fibroblast growth factor 1–4, platelet-derived growth factor receptor α and β, c-Kit and Ret. Anlotinib exerts inhibitory effects on tumor growth and angiogenesis.

B3336 | Anlotinib Hydrochloride DataSheet

Alternate Name/Synonyms: 1-(((4-((4-fluoro-2-methyl-1H-indol-5-yl)oxy)-6-methoxyquinolin-7-yl)oxy)methyl)cyclopropan-1-amine dihydrochloride AL-3818 AL3818

Appearance: Solid

Formulation:

CAS Number: 1360460-82-7

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₃H₂₄Cl₂FN₃O₃

Molecular Weight: 480.36

Cell-Permeable?: TRUE

Purity: ≥98%

Solubilities: DMSO

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Country of Origin: USA

Tag Line: A potent receptor tyrosine kinase (RTK) inhibitor

MDL Number:

PubChem CID: 57380530

SMILES: NC1(COC2=C(OC)C=C3C(OC4=C(F)C5=C(NC(C)=C5)C=C4)=CC=NC3=C2)CC1.[H]Cl.[H]Cl

InChi: InChI=1S/C23H22FN3O3.2ClH/c1-13-9-15-16(27-13)3-4-19(22(15)24)30-18-5-8-26-17-11-21(20(28-2)10-14(17)18)29-12-23(25)6-7-23;;/h3-5,8-11,27H,6-7,12,25H2,1-2H3;2*1H

InChi Key: UUAKQNIPIXQZFN-UHFFFAOYSA-N