LBD
ANP32E Antibody (N-term) [APG01889G]
- SKU:
- LBD-APG01889G
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Description
ANP32E Antibody (N-term) [APG01889G] | Gentaur UK, US & Europe Distribution
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H
Specificity: This ANP32E antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 31-64 amino acids from the N-terminal region of human ANP32E.
Cellular Localisation: Cytoplasm. Nucleus.
Molecular Weight: 30692
Clone: Polyclonal
Gene Name: ANP32E
Gene ID: 81611
Function: Histone chaperone that specifically mediates the genome-wide removal of histone H2A.Z/H2AZ1 from the nucleosome: removes H2A.Z/H2AZ1 from its normal sites of deposition, especially from enhancer and insulator regions. Not involved in deposition of H2A.Z/H2AZ1 in the nucleosome. May stabilize the evicted H2A.Z/H2AZ1-H2B dimer, thus shifting the equilibrium towards dissociation and the off-chromatin state (PubMed:24463511) . Inhibits activity of protein phosphatase 2A (PP2A) . Does not inhibit protein phosphatase 1. May play a role in cerebellar development and synaptogenesis.
Summary: Tissue Location: Expressed in peripheral blood leukocytes, colon, small intestine, prostate, thymus, spleen, skeletal muscle, liver and kidney.
Form: N/A
Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Application: WB
Dilution: WB--1:2000
Synonyms: Acidic leucine-rich nuclear phosphoprotein 32 family member E, LANP-like protein, LANP-L, ANP32E