Anterior gradient 2 homolog, human recombinant | P1154

AGR2 (Anterior gradient 2 homolog) is the human orthologue of the secreted Xenopus laevis Anterior Gradient protein(XAG-2). This is a small, possibly secreted molecule of yet weakly defined functions that is widely expressed in human tissues. Expression of AGR2 shows a positive correlation with expression of estrogen receptor in breast carcinoma and a negative correlation with expression of EGF receptor. Recombinant human AGR2, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

P1154 | Anterior gradient 2 homolog human recombinant DataSheet

Biomolecule/Target: AGR2

Synonyms: AGR 2, AG2, GOB-4, HAG-2, XAG-2

Alternates names: AGR 2, AG2, GOB-4, HAG-2, XAG-2

Taglines: Proto-oncogene that play a role in cell migration, cell differentiation and cell growth

NCBI Gene ID #: 5008

NCBI Gene Symbol: ONCM

Gene Source: Human

Accession #: P13725

Recombinant: Yes

Source: E.coli

Purity by SDS-PAGEs: 98%

Assay: SDS-PAGE

Purity: N/A

Assay #2: N/A

Endotoxin Level: N/A

Activity (Specifications/test method): N/A

Biological activity: The ED as determined by the dose-dependent stimulation of the proliferation of human TF-1 cells is <2 ng/ml, corresponding to a specific activity of >5 x 10 units/mg.

Results: N/A

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 26.0 kDa

Concentration: N/A

Appearance: Liquid

Physical form description: In 20 mM Tris 8.0, 1 mM DTT, 10% glycerol, 1 mM EDTA

Reconstitution Instructions: Reconstitute in HO to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or –20°C for future use.

Amino acid sequence: N/A