710
Anti- 14-3-3 Antibody | FNab00002
- SKU:
- 710-FNab00002-GEN
- Availability:
- In Stock - Delivery within a week
Description
Anti- 14-3-3 Antibody | FNab00002 | Gentaur UK, US & Europe Distribution
Form: liquid
Purification: Protein A+G purification
Purity: ≥95% as determined by SDS-PAGE
Host: Mouse
Clonality: monoclonal
Clone ID: 8D2
Isotype: IgG1
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: 14-3-3 theta (also known as YWHAQ, or 14-3-3 tau) is a member of 14-3-3 proteins which were the first phosphoserine/phosphothreonine-binding proteins to be discovered. 14-3-3 family members interact with a wide spectrum of proteins and possess diverse functions. Mammals express seven distinct 14-3-3 isoforms (gamma, epsilon, beta, zeta, sigma, theta, tau) that form multiple homo-and hetero-dimmers. 14-3-3 proteins display the highest expression levels in the brain, and have been implicated in several neurodegenerative diseases, including Alzheimer's disease and amyotrophic lateral sclerosis. This antibody was raised against full-length 14-3-3 theta.
Immunogen: tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide
synonyms: 14 3 3, 14 3 3 protein T cell, 14 3 3 protein tau, 14 3 3 protein theta, 1C5, HS1, Protein HS1, YWHAQ
Molecular weight (observed) : 28 kDa
Reactivity Species: Human, Mouse, Rat
Tested Application: ELISA, IF, IP, IHC, WB
Recomended Dillution : WB: 1:1000-1:10000; IHC: 1:20-1:200; IF: 1:20-1:200
Research Area: Neuroscience, Signal Transduction