Anti- 15 Lipoxygenase 2 Antibody | FNab00005

Anti- 15 Lipoxygenase 2 Antibody | FNab00005 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Immunogen affinity purified

Purity: ≥95% as determined by SDS-PAGE

Host: Rabbit

Clonality: polyclonal

Clone ID: N/A

Isotype: IgG

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: In humans, there are 6 functional lipoxygenases genes. Two of them encode for arachidonic acid 12-lipoxygenating (ALOX12, ALOX12B) and two for 15-lipoxygenating enzymes (ALOX15, ALOX15B) . ALOX15B has been described as the most abundant 15-lipoxygenating enzyme species in human carotid atherosclerotic lesions and to be associated with cerebrovascular symptoms. (PMID:24373925) . ALOX15B has 4 isoforms produced by alternative splicing with the MW of 76, 67, 69 and 73 kDa.

Immunogen: arachidonate 15-lipoxygenase, type B

synonyms: ALOX15B;Arachidonate 15-lipoxygenase B, 15-LOX-B, 15-LOX-2, Arachidonate 15-lipoxygenase type II, Linoleate 13-lipoxygenase 15-Lob

Molecular weight (observed) : 76 kDa

Reactivity Species: Human, Mouse, Rat

Tested Application: ELISA, IHC, IP, WB, IF

Recomended Dillution : WB: 1:200-1:2000; IHC: 1:20-1:200

Research Area: Metabolism