50

Anti 4-hydroxy-2-hexenal (4-HHE) monoclonal antibody

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SKU:: 50-MHH-030n-GEN
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Description
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Description

Anti 4-hydroxy-2-hexenal (4-HHE) monoclonal antibody

Description 4-hydroxy-2-hexenal (4-HHE):

4-hydroxy-2-alkenal is one of the major lipid peroxidation products, and shows many biological effects such as high toxicity to cells. Among them, 4-hydroxy-2-hexenal (HHE) is an aldehyde formed during peroxidation of n-3 fatty acids such as docosahexaenoic acid. HHE is highly reactive aldehyde and reacts with histidine residue of protein to form Michael-addition type adducts. This antibody is specific for HHE-histidine Michael adduct (HHE-His) and enable to detect HHE-His in the tissue samples.

Specifications

Clone #:	HHE53
Antigen:	HHE-modified keyhole-lympet hemocyanine
Specificity:	Specific for HHE-modified protein (especially HHE-His Michael adduct)
Subclass:	Mouse IgG_{1 kappa} Prepared as ascite, and protein-A purified.
Form:	Frozen in 10mM PBS containing 0.1% NaN₃ and 0.5% BSA.
Application:	Immunohistochemistry；It is recommended that the antibody be tried at 0.5-1.0 µg/mL on paraformaldehyde fixed tissue.
Storage:	Less than -20°C