50

Anti 8-OHdG monoclonal antibody

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SKU:
50-MOG-100P-GEN
Availability:
Usually ships in 5 working days
€3,198.00

Description

Anti 8-OHdG monoclonal antibody

About 8-hydroxy-2'-deoxyguanosine (8-OHdG):


Reactive oxygen species (ROS) and oxidative stress may be crucial for development of various diseases such as diabetes, cancer, and may play an important role in the aging process. 8-hydroxy-2'-deoxyguanosine (8-OHdG) is a product of oxidatively damaged DNA formed by hydroxy radical, singlet oxygen and direct photodynamic action. 8-OHdG can be detected in tissue, serum, urine and other biomaterials. Anti 8-OHdG monoclonal antibody (clone N45.1) is highly specific for DNA damage, not cross react with RNA oxidation products such as 8-hydroxy-guanine and 8-hydroxy-guanosine. Suitable for immunohistochemistry and ELISA.

Specifications
Clone #: N45.1
Antigen: 8-OHdG-conjugated Keyhole Limpet Hemocyanin
Subclass: Mouse IgG1(kappa)
Prepared as ascite, and ammnonium sulphate purified.
Form: Lyophilized Powder
Package: 20 or 100 µg of IgG / vial (MOG-020P and MOG-100P respectively).
Specificity: 19 analogues of 8-OHdG {guanosine (G), 7-methyl-G, 6-SH-G, 8-bromo-G, dA, dC, dT, dI, dU, dG, O6-methyl-dG, 8-OHdA, guanine (Gua), O6-methyl-Gua, 8-OHGua, uric acid, Urea, creatine, creatinine} demonstrate no cross-reactivity. Only 8-sulfhydryl-G and 8-OHG demonstrate minimal cross-reactivity (less than 1%).
Use: Immunohistochemistry and ELISA
Storage: Less than -20°C for 5 years
When transport, stable at least 7 days at room temperature.
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Additional Information

Size:
100 ug of IgG/vial
Type of Marker:
DNA Oxidation
Marker:
TG
Storage:
Less than -20°C
Usage:
Tissue
Application:
Immunohistochemistry
Remark:
DNA-specific oxidative stress marker.
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