Description
The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. The organ- and cell-specific expression of this gene suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronavirus HCoV-NL63 and the human severe acute respiratory syndrome coronaviruses, SARS-CoV and SARS-CoV-2 (COVID-19 virus)
A2072 | Anti-ACE2 Antibody DataSheet
Antibody Target: ACE2
Target Alternative Name: Angiotensin-converting enzyme 2; ACE-related carboxypeptidase; Angiotensin-converting enzyme homolog; ACEH; Metalloprotease MPROT15
Tag Line: Rabbit polyclonal antibody to detect ACE2 expression in human samples
Category: Primary antibody
Host: Rabbit
Isotype: IgG
Species Reactivities: Human
Immunogen Sequence: Recombinant Human Angiotensin-converting enzyme 2 protein (395-638 aa)
Accession #: Q9BYF1
Gene ID: 59272
Appearance: Colorless liquid
Form: Liquid
Concentration:
Formulation: In 0.01 M PBS, pH 7.4, 50% Glycerol, 0.03% proclin 300
Purification: Affinity purified
Application: Immunohistochemistry (IHC),Immunofluorescence (IF)
Positive Control:
Application And Usages: IHC 1:20-1:200, IF 1:50-1:200
Country of Animal Origin: USA
Country of Manufacture: USA
Usage: For Research Use Only! Not to be used in humans.
Handling: The antibody solution should be gently mixed before use.
Western Blot Verified: FALSE
Immunocytochemistry Verified: FALSE
Immunofluorescence Verified: TRUE
Immunoprecipitation Verified: FALSE
FACS Verified: FALSE
ELISA Verified: FALSE
ChIP Verified: FALSE
Dot Blot Verified: FALSE
Flow Cytometry Verified: FALSE
Additional Information
Size: |
100 ug |
Storage Condition: |
-20ºC |
Shipping Condition: |
Gel Pack |
Shelf Life: |
12 months |