Anti-ADAR1 Antibody | A2035

Double-stranded RNA-specific adenosine deaminase (ADAR1) encodes the enzyme that is responsible for destabilization of double-stranded RNA by deaminating adenosine to inosine in non-coding repetitive elements and short interspersed nuclear elements. ADAR1 is known to be expressed in embryonic cells and adult tissues and is responsible for the maturation and differentiation of these cells and tissues. ADAR1 also plays an essential role in the maintenance of hematopoietic stem cells. Several isoforms of ADAR1 exist, which includes a full-length protein (150 kDa) and two short functionally active isoforms (80 and 110 kDa).

A2035 | Anti-ADAR1 Antibody DataSheet

Antibody Target: ADAR1

Target Alternative Name: ADAR1; DSRAD; G1P1; IFI4; Double-stranded RNA-specific adenosine deaminase; DRADA; 136 kDa double-stranded RNA-binding protein; p136; Interferon-inducible protein 4; IFI-4; K88DSRBP

Tag Line: Affinity purified rabbit polyclonal antibody to detect expression of Double-stranded RNA-specific adenosine deaminase in human, mouse, rat and porcine samples

Category: Antibody

Host: Rabbit

Isotype: IgG

Species Reactivities: Porcine, Rat, Mouse, Human

Immunogen Sequence: KLH-conjugated synthetic peptide targeting a sequence within the C-term region of human ADAR1

Accession #: P55265

Gene ID: 103

Appearance: Colorless liquid

Form: Liquid

Concentration:

Formulation: In 0.42% Potassium phosphate; 0.87% NaCl; pH 7.3; 30% glycerol; and 0.01% sodium azide

Purification: Affinity purified

Application: Immunohistochemistry (IHC), Western Blotting

Positive Control:

Application And Usages: WB 1:500 - 1:1000, IHC 1:100 - 1:200

Country of Animal Origin: USA

Country of Manufacture: USA

Usage: For Research Use Only! Not to be used in humans.

Handling: The antibody solution should be gently mixed before use.

Western Blot Verified: WB data verified using Jurkat, Ramos and HeLa cell lysates

Immunocytochemistry Verified: True

Immunofluorescence Verified: False

Immunoprecipitation Verified: False

FACS Verified: False

ELISA Verified: False

ChIP Verified: False

Dot Blot Verified: False

Flow Cytometry Verified: False