710
Anti- ADIPOQ Antibody | FNab00170
- SKU:
- 710-FNab00170-GEN
- Availability:
- In Stock - Delivery within a week
Description
Anti- ADIPOQ Antibody | FNab00170 | Gentaur UK, US & Europe Distribution
Form: liquid
Purification: Protein A+G purification
Purity: ≥95% as determined by SDS-PAGE
Host: Mouse
Clonality: monoclonal
Clone ID: 6E1
Isotype: IgG2a
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: Important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. Inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. May play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex, LMW, MMW or HMW.
Immunogen: adiponectin, C1Q and collagen domain containing
synonyms: ACDC, ACRP30, adiponectin, ADIPOQ, ADIPQTL1, ADPN, APM 1, APM1, GBP28, Gelatin binding protein
Molecular weight (observed) : 26 kDa
Reactivity Species: Human, Mouse
Tested Application: ELISA, WB, IHC
Recomended Dillution : WB: 1:500-1:2000
Research Area: Signal Transduction, Metabolism