Anti- Aldolase C Antibody | FNab00304

Anti- Aldolase C Antibody | FNab00304 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Protein A+G purification

Purity: ≥95% as determined by SDS-PAGE

Host: Mouse

Clonality: monoclonal

Clone ID: 6F3

Isotype: IgG1

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: Fructose-bisphosphate aldolase C (ALDOC) reversibly cleaves FBP and F1-P to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate and is strongly expressed in mammalian brain together with ALDOA and is alsopresent in the heart and spleen of some species (PMID:9363598) . It is involed in glycolysis as an important enzyme. Phospholipase D2 and inositol 1, 4, 5-triphosphate interact with ALDOC in signal transduction. Meanwhile, the protein expression of ALDOC has been reported to be regulated in brain tumor, hepatomas, and lung cancer (PMID:21548097) .

Immunogen: aldolase C, fructose-bisphosphate

synonyms: ALDOC, Aldolase C, Brain type aldolase, Fructose bisphosphate aldolase C

Molecular weight (observed) : 39 kDa

Reactivity Species: Human

Tested Application: ELISA, WB, IF

Recomended Dillution : WB: 1:5000-1:50000; IHC: 1:50-1:500; IF: 1:20-1:200

Research Area: Metabolism