Anti- Amylin Antibody | FNab00384

Anti- Amylin Antibody | FNab00384 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Immunogen affinity purified

Purity: ≥95% as determined by SDS-PAGE

Host: Rabbit

Clonality: polyclonal

Clone ID: N/A

Isotype: IgG

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: IAPP, also known as Amylin, is commonly found in pancreatic islets of patients suffering diabetes mellitus type II, or harboring an insulinoma. IAPP is co-secreted with insulin by pancreatic β-cells and largely contributes to glycemic control. Studies suggest that this protein, like the related beta-amyloid (Abeta) associated with Alzheimer's disease, can induce apoptotic cell-death in particular cultured cells, an effect that may be relevant to the development of type II diabetes.

Immunogen: islet amyloid polypeptide

synonyms: Amylin, DAP, Diabetes associated peptide, IAP, IAPP, Insulinoma amyloid peptide, islet amyloid polypeptide

Molecular weight (observed) : 10 kDa

Reactivity Species: Human

Tested Application: ELISA, WB, IHC, IF

Recomended Dillution : IHC: 1:20-1:200

Research Area: Signal Transduction