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Anti-ANXA7 Antibody | A1750
- SKU:
- 26-A1750-100-GEN
- Availability:
- Usually shipped in 5 working days
Description
Annexin VII is a member of the annexin family of calcium-dependent phospholipid binding proteins. The Annexin VII gene contains 14 exons and spans approximately 34 kb of DNA. An alternatively spliced cassette exon results in two mRNA transcripts of 2.0 and 2.4 kb which are predicted to generate two protein isoforms differing in their N-terminal domain. The alternative splicing event is tissue specific and the mRNA containing the cassette exon is prevalent in brain, heart and skeletal muscle. The transcripts also differ in their 3'-non coding regions by the use of two alternative poly(A) signals. Annexin VII encodes a protein with a molecular weight of approximately 51 kDa with a unique, highly hydrophobic N-terminal domain of 167 amino acids and a conserved C-terminal region of 299 amino acids. The latter domain is composed of alternating hydrophobic and hydrophilic segments. Structural analysis of the protein suggests that Annexin VII is a membrane binding protein with diverse properties, including voltage-sensitive calcium channel activity, ion selectivity and membrane fusion.
A1750 | Anti-ANXA7 Antibody DataSheet
Antibody Target: Annexin A7
Target Alternative Name: Annexin A7, Annexin VII, SNX, Synexin
Tag Line: Polyclonal antibody to detect Anti-ANXA7 Antibody in human and mouse samples.
Category: Signal Transduction
Host: Rabbit
Isotype: IgG
Species Reactivities: Mouse, Human
Immunogen Sequence: Recombinant protein of human ANXA7
Accession #: P20073
Gene ID: 310
Appearance: Colorless liquid
Form: Liquid
Concentration: 0.9 mg/ml
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Application: Immunohistochemistry (IHC), ELISA
Positive Control:
Application And Usages: IHC 1:50-1:200
Country of Animal Origin: USA
Country of Manufacture: USA
Usage: For Research Use Only! Not to be used in humans.
Handling: The antibody solution should be gently mixed before use.
Western Blot Verified: True
Immunocytochemistry Verified: True
Immunofluorescence Verified: False
Immunoprecipitation Verified: False
FACS Verified: False
ELISA Verified: False
ChIP Verified: False
Dot Blot Verified: False
Flow Cytometry Verified: False
Additional Information
Size: |
100 uL |
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
12 months |