Anti- AP3B2 Antibody | FNab00464

Anti- AP3B2 Antibody | FNab00464 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Immunogen affinity purified

Purity: ≥95% as determined by SDS-PAGE

Host: Rabbit

Clonality: polyclonal

Clone ID: N/A

Isotype: IgG

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: Subunit of non-clathrin-and clathrin-associated adaptor protein complex 3 (AP-3) that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.

Immunogen: adaptor-related protein complex 3, beta 2 subunit

synonyms: AP 3 complex subunit beta 2, AP3B2, Beta 3B adaptin, DKFZp686D17136, NAPTB

Molecular weight (observed) : 120-140 kDa

Reactivity Species: Human, Mouse, Rat

Tested Application: ELISA, WB, IF, IP

Recomended Dillution : WB: 1:200-1:2000 IP: 1:200-1:2000

Research Area: Signal Transduction, Metabolism