Anti-APIP Antibody | A1766

APIP is an APAF1 (MIM 602233)-interacting protein that acts as a negative regulator of ischemic/hypoxic injury.The protein highly expressed in skeletal muscle and heart and binds to the CARD of Apaf-1 in competition with caspase-9. Exogenous APIP inhibits cytochrome c-induced activation of caspase-3 and caspase-9, and suppresses cell death triggered by mitochondrial apoptotic stimuli through inhibiting the downstream activity of cytochrome c released from mitochondria.

A1766 | Anti-APIP Antibody DataSheet

Antibody Target: APAF1-interacting protein

Target Alternative Name: Apaf1 Interacting Protein, APIP2, CG129, Monocyte/macrophage protein 19, MTNB, dJ179L10.2

Tag Line: Polyclonal antibody to detect APIP in human and mouse samples.

Category: Cell Proliferation

Host: Rabbit

Isotype: IgG

Species Reactivities: Mouse, Human

Immunogen Sequence: Recombinant protein of human APIP

Accession #: Q96GX9

Gene ID: 51074

Appearance: Colorless liquid

Form: Liquid

Concentration: 0.2 mg/ml

Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3

Purification: Affinity purification

Application: Immunohistochemistry (IHC), Western Blotting

Positive Control:

Application And Usages: WB 1:200-1:1000, IHC 1:25-1:100

Country of Animal Origin: USA

Country of Manufacture: USA

Usage: For Research Use Only! Not to be used in humans.

Handling: The antibody solution should be gently mixed before use.

Western Blot Verified: True

Immunocytochemistry Verified: False

Immunofluorescence Verified: False

Immunoprecipitation Verified: False

FACS Verified: False

ELISA Verified: False

ChIP Verified: False

Dot Blot Verified: False

Flow Cytometry Verified: False