Description
APIP is an APAF1 (MIM 602233)-interacting protein that acts as a negative regulator of ischemic/hypoxic injury.The protein highly expressed in skeletal muscle and heart and binds to the CARD of Apaf-1 in competition with caspase-9. Exogenous APIP inhibits cytochrome c-induced activation of caspase-3 and caspase-9, and suppresses cell death triggered by mitochondrial apoptotic stimuli through inhibiting the downstream activity of cytochrome c released from mitochondria.
A1766 | Anti-APIP Antibody DataSheet
Antibody Target: APAF1-interacting protein
Target Alternative Name: Apaf1 Interacting Protein, APIP2, CG129, Monocyte/macrophage protein 19, MTNB, dJ179L10.2
Tag Line: Polyclonal antibody to detect APIP in human and mouse samples.
Category: Cell Proliferation
Host: Rabbit
Isotype: IgG
Species Reactivities: Mouse, Human
Immunogen Sequence: Recombinant protein of human APIP
Accession #: Q96GX9
Gene ID: 51074
Appearance: Colorless liquid
Form: Liquid
Concentration: 0.2 mg/ml
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Application: Immunohistochemistry (IHC), Western Blotting
Positive Control:
Application And Usages: WB 1:200-1:1000, IHC 1:25-1:100
Country of Animal Origin: USA
Country of Manufacture: USA
Usage: For Research Use Only! Not to be used in humans.
Handling: The antibody solution should be gently mixed before use.
Western Blot Verified: True
Immunocytochemistry Verified: False
Immunofluorescence Verified: False
Immunoprecipitation Verified: False
FACS Verified: False
ELISA Verified: False
ChIP Verified: False
Dot Blot Verified: False
Flow Cytometry Verified: False
Additional Information
Size: |
100 uL |
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
12 months |