710
Anti- ASZ1 Antibody | FNab00653
- SKU:
- 710-FNab00653-GEN
- Availability:
- In Stock - Delivery within a week
Description
Anti- ASZ1 Antibody | FNab00653 | Gentaur UK, US & Europe Distribution
Form: liquid
Purification: Immunogen affinity purified
Purity: ≥95% as determined by SDS-PAGE
Host: Rabbit
Clonality: polyclonal
Clone ID: N/A
Isotype: IgG
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process. Required prior to the pachytene stage to facilitate the production of multiple types of piRNAs, including those associated with repeats involved in the regulation of retrotransposons. May act by mediating protein-protein interactions during germ cell maturation (By similarity) .
Immunogen: ankyrin repeat, SAM and basic leucine zipper domain containing 1
synonyms: ALP1, ANKL1, Ankyrin like protein 1, ASZ1, C7orf7, GASZ, Orf3
Molecular weight (observed) : 48-50kd
Reactivity Species: Human, Mouse, Rat
Tested Application: ELISA, WB, IHC
Recomended Dillution : WB: 1:500-1:2000
Research Area: Cardiovascular, Signal Transduction