Anti- BCL2L2 Antibody | FNab10311

Anti- BCL2L2 Antibody | FNab10311 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Immunogen affinity purified

Purity: ≥95% as determined by SDS-PAGE

Host: Rabbit

Clonality: polyclonal

Clone ID: N/A

Isotype: IgG

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: This gene encodes a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators. Expression of this gene in cells has been shown to contribute to reduced cell apoptosis under cytotoxic conditions. Studies of the related gene in mice indicated a role in the survival of NGF- and BDNF-dependent neurons. Mutation and knockout studies of the mouse gene demonstrated an essential role in adult spermatogenesis. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream PABPN1 (poly (A) binding protein, nuclear 1) gene.

Immunogen: BCL2-like 2

synonyms: BCL-W, BCL2-L-2, BCLW, PPP1R51

Molecular weight (observed) : 21 kDa

Reactivity Species: Human, Mouse, Rat

Tested Application: ELISA, IHC

Recomended Dillution : WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

Research Area: N/A