710
Anti- BUB3 Antibody | FNab00988
- SKU:
- 710-FNab00988-GEN
- Availability:
- In Stock - Delivery within a week
Description
Anti- BUB3 Antibody | FNab00988 | Gentaur UK, US & Europe Distribution
Form: liquid
Purification: Immunogen affinity purified
Purity: ≥95% as determined by SDS-PAGE
Host: Rabbit
Clonality: polyclonal
Clone ID: N/A
Isotype: IgG
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: Has a dual function in spindle-assembly checkpoint signaling and in promoting the establishment of correct kinetochore-microtubule (K-MT) attachments. Promotes the formation of stable end-on bipolar attachments. Necessary for kinetochore localization of BUB1. Regulates chromosome segregation during oocyte meiosis. The BUB1/BUB3 complex plays a role in the inhibition of anaphase-promoting complex or cyclosome (APC/C) when spindle-assembly checkpoint is activated and inhibits the ubiquitin ligase activity of APC/C by phosphorylating its activator CDC20. This complex can also phosphorylate MAD1L1.
Immunogen: budding uninhibited by benzimidazoles 3 homolog (yeast)
synonyms: N/A
Molecular weight (observed) : N/A
Reactivity Species: Human, Mouse, Rat
Tested Application: ELISA, IHC, WB
Recomended Dillution : IF: 1:20-1:200
Research Area: Cell Division and Proliferation